Topotecan Hycamptin

Learn about your cancer drugs.


This chemotherapy and cancer drugs article is about Topotecan (Hycamptin) which is a chemotherapy drug primarily used to treat ovarian cancer, but also small cell lung cancer and acute myeloid leukaemia

It is a topoisomerase 1 inhibitor, which works by blocking the topoisomerase 1 enzyme, which helps to separate and repair the DNA in cells when they divide.  Blocking the action of this enzyme damages the DNA and so the cells cannot continue to grow. 

Topotecan is administered through a drip intravenously.

Side effects can include: fatigue, greater risk of infections, anaemia, bruising and bleeding, nausea and vomiting, temporary hair loss or thinning, diarrhoea or constipation, mouth ulcers.

Other articles that you may find interesting are:

  1. Diet for Chemotherapy ;

  2. Beneficial bacteria ;

  3. A-Z guide to complementary therapies;

  4. Your cancer, where you can read about everything from causes to cancer treatments to complementary therapies for your cancer.

  5. How to boost your immune system.

To return to the drug list, click here.

Learn about your cancer drugs.
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