Sunitinib Sutent

Learn about your cancer drugs.

Surgery

This chemotherapy and cancer drugs article is about Sunitinib (Sutent) which is used to treat advanced kidney cancer and a rare kind of cancer called a gastrointestinal stromal tumour (GIST) that occurs in the wall of the stomach and small intestine. GIST tumours are caused by a particular abnormal tyrosine kinase, called c-kit. Sunitinib blocks the action of this enzyme, which stops the GIST cells from multiplying uncontrollably.

Sunitinib is a multi-kinase inhibitor. It works by interfering with the pathways that signal certain cancer cells to grow. In kidney cancer, higher than normal amounts of a type of kinase called vascular endothelial growth factor (VEGF) are made. VEGF stimulates the production of blood vessels, and so helps the cancer to grow. Sunitinib blocks the activity of VEGF.

Side effects can include: fatigue, swelling in the palms of the hands and soles of the feet, mouth ulcers, hair and skin colour changes and hair thinning, high blood pressure, diarrhoea, mild nausea, bleeding and bruising. Rarely there may be heart and thyroid problems and blood clots.

Other articles that you may find interesting are:


  1. Diet for Chemotherapy ;

  2. Beneficial bacteria ;

  3. A-Z guide to complementary therapies;

  4. Your cancer, where you can read about everything from causes to cancer treatments to complementary therapies for your cancer.

  5. How to boost your immune system.

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Learn about your cancer drugs.
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