Polyphenol compounds and Pomi-T highly effective against cancer

Polyphenol compounds and Pomi-T highly effective against cancer

   

Polyphenol compounds ‘highly effective against cancer’ - now clinical trials with prostate cancer

 

 

Addenbrook’s oncologist Robert Thomas and Pomi-T

 

Professor Robert Thomas and his research team have completed a randomised double blind, placebo controlled trial of an antioxidant-rich dietary food supplement in men with prostate cancer.  Professor Thomas is the Consultant Oncologist at Cranfield University and Bedford & Addenbrooke’s, NHS Hospital Trusts.


‘This scientifically robust study aims to establish whether boosting the diet with a food supplement rich in plant chemicals (polyphenols),which have antioxidant and other potential anti-cancer properties, has an influence on PSA progression compared to placebo. Epidemiological and large cohort studies support the paradigm that antioxidant-rich diets reduce the risk of prostate cancer (Giovannucci et al 2002). More recently prospective studies show that diet and lifestyle may also benefit men with established disease by slowing or halting PSA progression (Ornish 2005, Thomas 2008).  


A review of the international literature has highlighted green tea, pomegranate, broccoli and curcumin as those with some of the best evidence for a positive affect on PSA (Thomas et al 2011). Past studies, however, have involved small numbers of participants, not been randomised or placebo controlled, and hence are not regarded as scientifically vigorous but despite this, up to 70% of men have been reported to take some form of nutritional supplement after a diagnosis of prostate cancer’ says the study introduction’ it says in the research study introduction.


200 men with prostate cancer took the supplement, called Pomi-T, comprised of green tea, curcumin/turmeric, broccoli and pomegranate, or a placebo. At the end

of a six-month trial, their PSA levels - a protein which is an indicator of the cancer - were 63 per cent lower than those who took a placebo. At CANCERactive we have detailed coverage of the benefits of each of these bioactive natural ingredients, and more. 

 

For supplies of Robert’s Pomi-T you might consider the Natural Selection shop (Click here)    

 

  

 

                                                                
The American Chemical Society endorse claims for polyphenols and cancer too


Studies have also linked the regular intake of polyphenols with lower risks of many cancers including breast, pancreatic, oesophageal, ovarian, prostate, and skin cancer.


Research has also found that breast cancer survivors eating polyphenol-rich fruit, vegetables, soy and green tea were found to have lower relapse rates.


The anti-cancer effect of polyphenols works because of their anti-oxidant properties, which protect the DNA from oxidative damage from carcinogens. Polyphenols can also actually kill cancer cells and inhibiting their proliferation.


Polyphenols are found in more than 700 foods, primarily in most fruits and vegetables, herbs and spices and even nuts and cocoa products. Many are considered superfoods. Top providers are foods like blueberries, apricots,  grapes, olives and olive oil, artichoke, herbs such as oregano, peppermint and cloves, with nuts and seeds like walnuts, almonds and flaxseed, green tea and even dark chocolate in the top 30.


In September 2013 the American Chemical Society (ACS) held a symposium, "Polyphenolic Chemistry in Food Science: Flavor, Color, and Biofunctional Properties," as part of its 246th National Meeting & Exposition. For anybody who has read ‘The Rainbow Diet’ by Chris Woollams (which first appeared in 2006) their conclusions of ‘having significant health benefits even with cancer’ are nothing new.

 

ACS presented 12 papers and confirmed everything we have told you in the past. For example:

 

1. Polyphenols are anti-inflammatory and can also help prevent cancer from forming.
2. Red grape polyphenols like resveratrol inhibit aggressive oestrogen attacks in breast cancer and have been shown to kill cancer cells. They have been shown to help prevent dementia and even Alzheimer’s.
3. Polyphenols in Pomegranates have been shown to restrict prostate cancer and prevent its growth.

4. Polyphenols in green vegetables like broccoli have been shown capable of denaturing aggressive oestrogen, and attacking cancer causing pathways. They can even reduce toxin damage to DNA.

5.  Pterostilbene, (in blueberries and grapes) has an anti-cancer effect and reduces nervous disorders.

6.  Green and black tea are high in polyphenols and can inhibit cancer cell formation and boost the immune system significantly. Perth Medical School has shown a positive effect in a number of cancers.

 

 

As we have frequently told you, an essential part of the fight against cancer is a healthy microbiome (or gut flora), and this was highlighted by one of the presentations at the ACS conference. Researchers showed that the gut bacteria used polyphenols to release compounds that reduced inflammation and even prevented cancer. 


There is much more in Cancer Watch on the benefits of bioactive natural compounds - if you just simply run down the list of titles in 2012 and 2013 you will be very surprised!


Professor Thomas is now marketing his polyphenol product. You might like to look at the Natural Selection shop to see the sizes available and prices (Click Here).

 

 

 

EDITOR’S COMMENT: 

We are not in the slightest surprised by the success of Pomi-T. If anything, we think it could have had one or two more ingredients and been even better! But then, it was only concerned with one group of bioactive natural compounds – polyphenols. These columns have been consistent about the benefits of the above bioactive compounds and others:


1. Indole3carbinol/DIM – found in broccoli and known to have two separate benefits: Firstly, to denature and block the action of aggressive oestrogen, a key component in prostate and other cancers; Secondly, via a completely separate biochemical pathway it can inhibit cancer cell proliferation (CLICK HERE)


2. Curcumin -  what doesn’t it do? The most researched compound of any in the field of cancer, including drugs! We have covered research that it stops inflammation, metastases in prostate cancer (CLICK HERE) and cancer cell proliferation (CLICK HERE). Please note: the American Cancer Society recommends that, for better absorption, curcumin is taken with extra-Virgin Olive Oil and black pepper – the active ingredient, piperine, also has anti-cancer benefits.


3. Pomegranate – we have covered research that pomegranate has specific anti-cancer benefits with prostate cancer - stopping metastases and killing cancer cells (CLICK HERE).


4. Green Tea – Perth Medical School have produced a number of studies showing the benefits (particularly preventative) of the active ingredient EGCG. In one study the Mayo clinic reported that 4-7 cups a day stopped leukaemia in its tracks. Although we fear this claim is a bit excessive it at least shows the products potential. (CLICK HERE).


All these compounds are featured in both the Rainbow Diet and Everything you need to know to help you beat cancer. They would be applicable to many cancers and fit the American Cancer Society’s 2012 report that diet, weight control and daily exercise can increase survival and even prevent a cancer returning.
So there are other things you might consider, for example:


5. Vitamin D3 or spending time in the sunshine,


6. Sulphoraphanes also found in small amounts in broccoli and especially its seeds (CLICK HERE)


7. Lycopene (tomatoes) especially if you have prostate cancer,


8. Resveratrol – seems to work synergistically with curcumin and green tea, although it has significant anti-cancer properties of its own,


9. Coenzyme Q10 especially if you are over 50,


10. Multi-strained probiotics, polyphenols interact with them to do their work,


11. Being at the correct weight for your height and body type,


12. Reducing glucose and salt consumption, while increasing potassium and magnesium intake,


AND DON’T FORGET ... Doing light but daily exercise for 30 minutes a day.


 

 


The above are all in line with the recommendations, published in these columns, of the National Cancer Institute researchers.  We have all this covered in detail elsewhere on this website. As a start we recommend you read both ‘Everything you need to know to help you beat cancer’, and, ‘The Rainbow Diet’Click Here for details.   

2013 Research
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