Irinotecan Campto

Learn about your cancer drugs.


This chemotherapy and cancer drugs article is about Irinotecan (Campto) which is used to treat bowel cancer, generally given in combination with other chemotherapy drugs 5FU and Leucovorin (folinic acid). It is administered intravenously.  It is made from a plant alkaloid known as a topoisomerase I inhibitor. It is thought to work by blocking the action of that enzyme within the cells.  Blocking this enzyme leads to breaks in the DNA, which leads to cell death. Because cancer cells divide more rapidly than normal cells, they are more likely than normal cells to be affected by this.

Side effects can include: fatigue, acute cholinergic syndrome (Increased sweating, production of saliva, stomach cramps and diarrhoea) which can be drug controlled, diarrhoea, nausea and vomiting.

Other articles that you may find interesting are:

  1. Diet for Chemotherapy ;

  2. Beneficial bacteria ;

  3. A-Z guide to complementary therapies;

  4. Your cancer, where you can read about everything from causes to cancer treatments to complementary therapies for your cancer.

  5. How to boost your immune system.

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Learn about your cancer drugs.
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