Sulphoraphanes, or sulforaphanes in research

2013 Research


Sulphoraphanes, or sulforaphanes, kill cancer cells

Hidden inside every stalk of broccoli and every floret of cauliflower is a substance so powerful at preventing and treating cancer that not even the drug industry is capable of matching its efficacy, both in terms of safety and potency. And researchers are still continuing to uncover the amazing medicinal power of sulphoraphane, a therapeutic compound found in cruciferous vegetables that most recently was discovered to prevent and treat leukaemia. Sulphoraphane, (in America sulforaphane) is a known Epigenetic - it can modify the environment of the DNA allowing genes to become unblocked, meaning they can express themselves as nature intended!



Researchers from the Baylor College of Medicine in Texas recently tested the effects of an isolated and highly concentrated form of sulforaphane on both mouse and human cell lines affected by acute lymphoblastic leukaemia, a type of cancer that afflicts white blood cells, and most commonly in children. Led by Dr. Koramit Suppipat, the study involved applying sulforaphane to leukaemic cell lines and primary lymphoblasts obtained from paediatric patients for the purpose of assessing its effects.



Upon observation, it was learned that sulforaphane effectively eradicates cancer cells by entering them and reacting with certain internal proteins to induce apoptosis, or cell death. At the same time, researchers observed that sulforaphane did not harm healthy cells when applied to cell lines obtained from healthy, cancer-free patients, a phenomenon unique to natural, therapeutic compounds that have not been artificially manipulated for the purpose of trying to patent a specific medicinal compound.

Sulphoraphanes and polyphenols are two of the main bioactive and epigenetic food groups underpinning the strength of The Rainbow Diet.



"There is about an 80 per cent cure rate (for acute lymphoblastic leukemia), but some children don’t respond to treatment. For those cases, we are in need of alternative treatments," explained Dr. Daniel Lacorazza, an assistant professor of pathology and immunology at Baylor, and one of the study’s contributors. "Sulforaphane is a natural product. However, what we used in this study is a concentrated purified form".


2013 Research
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