Epigenetic benefits of conjugated linoleic acid, CLA, with breast cancer

2014 Research

Eating meat from organic grass-fed cattle or ruminants may well have anti-cancer and anti-tumour effects because of the high levels of conjugated linoleic acid (CLA) and the finding that this has strong epigenetic effects and is regulatory on a number of breast cancer pathways.

Scientists from Ohio State (Li-Shu Wang, Yi-Wen Huang, Weiping Ye, Suling Liu, Pearlly Yan and Young Lin) have been researching Conjugated Linoleic Acid which is produced in the rumens of grass fed cattle.

In a study ‘Epigenetic modifications of conjugated linoleic acid (CLA) on tumor suppressor gene and protein tyrosine phosphatase’ which looked at breast cancer, they concluded that ‘It is noteworthy that a natural food component produced from the fermentation of rumen bacterium in food-producing ruminants such as beef and dairy cattle has health significance to the consumers at large and also for chemoprevention purposes. The beneficial effects of low level and long-term daily consumption of CLA-enriched beef and dairy products may serve as potent natural demethylation compounds.’

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Methylation causes the changes in bonds around the DNA (often inaccurately called ‘mutation’), which prevent genes being expressed properly. 

The Science of Epigenetics has shown that many natural compounds can affect this methylation process and unblock genes, thus correcting the cancer process. 

This is not the first time that Conjugated Linoleic Acid (CLA) has been shown to have protective and corrective benefits with breast cancer.

Go to: Review of CLA with cancer and health

"If you are already thinking of buying CLA as a supplement, it might be interesting to see what’s on offer in the ’Our Natural Selection’ store. (Click here)"

2014 Research
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