Rose hips slow TNBC spread
Triple negative breast cancer (TNBC) is a particularly worrying form of breast cancer as oncologists have no protocol to treat, let alone cure, it. The disease tends to be more aggressive and attack younger women, and African-Americans.
(FASEB) in Boston, suggest that the extract from rosehips — the fruit of the rose plant — significantly reduced the growth and migration of cells from triple-negative breast cancer (TNBC).
According to a presentation at FASEB in Boston, researchers led by Patrick Martin, PhD, associate professor of biology at North Carolina Agricultural and Technical State University (NCATSU) in Greensboro, treated tissue cultures of TNBC cells with several concentrations of rose hip extract. Exposure to the highest concentration (1.0 mg/ml) decreased TNBC-cell proliferation by 50%. It appears to work by reducing MAPK and Akt, two enzymes that are known to promote cell growth in triple negative breast cancer.
Previous work suggested Rose hip extract stopped cancer spreading to, and in, the brain.
Go To: Review - Bioactive compound and Triple negative breast cancer
In the past in Cancer Watch we have covered research studies for vitamin D, curcumin and indole 3 carbinol, each of which seems to restrict proliferation of TNBC cells.
1. Ref: 2014: http://cancerres.aacrjournals.org/content/74/19_Supplement/3213
2. Ref : ScienceDaily. (2015). Natural extract shows promise for preventing breast cancer, study suggests.