Triclosan alters hormone regulation, bacterial resistance and may lead to liver damage

Triclosan alters hormone regulation, bacterial resistance and may lead to liver damage

Triclosan [5-chloro-2-(2,4-dichlorophenoxy) phenol or TCS is one of the most common additives in consumer products; it is used for its anti-microbial properties having been first approved by the FDA as a pesticide.

Its widespread use finds it polluting various aspects of the environment, and repeated studies show it regularly in humans. According to the Mayo Clinic, one 2008 study found it in the blood streams of 75% of adults and children.

Researchers reporting in the Proceedings of the National Academy of Sciences in the USA have found that  “TCS enhances hepatocyte proliferation, fibrogenesis, and oxidative stress, which, we believe, can be the driving force for developing advanced liver disease”.

The study was conducted in mice, but researchers concluded that there would be a similar risk to humans, even to the point of liver cancer.

The FDA currently states on its website that it engaged in an ongoing safety review with humans. “Animal studies have shown that triclosan alters hormone regulation. However, data showing effects in animals don’t always predict effects in humans. Other studies in bacteria have raised the possibility that triclosan contributes to making bacteria resistant to antibiotics.”

There is also research suggesting it damages the immune system and elsewhere on this website we have reported that it may cause muscle damage.

The antibacterial and pesticide benefits see its use in a wide variety of soaps and body washes.

Worryingly, it is used in some mouthwash products and even some toothpastes. The FDA website states “In 1997, FDA reviewed extensive effectiveness data on triclosan in Colgate Total toothpaste. The evidence showed that triclosan in this product was effective in preventing gingivitis”.

Well, that’s OK then!! But it hardly seems a smart choice to put into a product you put in your mouth!


2015 Research
CancerAcitve Logo
Subscribe (Free e-Newsletter)

Join Chris'

Join Chris' NewsletterSignup today for free and be the first to get notified on new updates.