The Care Oncology Clinic, COC

The Care Oncology Clinic, COC

Care Oncology have designed an off-label drug protocol, the COC protocol, to enhance the standard of care for cancer treatment and improve survival times; it involves an attack on the metabolism of cancer cells and their ability to feed and spread. 

Care Oncology launched in 2014 using four drugs off-label with the aim of restricting a cancer’s ability to feed and grow.

"These medicines target cholesterol, glucose and the glycolysis process, which impact on the metabolism of cancer cells and the immune cells around them"


What is an off-label drug?

When a drug is approved by NICE or the FDA for use, it has been through Clinical Trials showing it performs. It cuts blood sugar in diabetics; it kills parasites in humans. And so the label on the bottle details what it should be used for.

However, once a drug is approved, a doctor is reasonably free to prescribe it for anything. This is using the drug 'Off-label’ for something actually not originally approved. It is done with steroids all the time in Hospitals they even get used to stimulate appetite. But they are not approved for that use.


The Care Oncology Protocol, or COC Protocol 

The Care Oncology Protocol, which is patented and trade-marked, uses four common medicines, not originally intended for cancer treatment. These medicines have been fully tested and approved for use in humans and their side-effects are well established.

"All of the medications used in the COC protocol are well-understood and have few side-effect according to Care Oncology."

The medicines are:

* Metformin an oral diabetes medicine that helps control blood sugar, particularly in people who are overweight. Care Oncology usually use 500 mg, twice per day.

Go to: Metformin in cancer treatment

* Atorvastatin also called Lipitor. A statin used to treat people with abnormally high lipid levels, especially LDL and triglycerides, i.e. 'bad’ fat. It is Lipophilic and so crosses membranes reducing lipids in the blood and also in the tissues. Care Oncology usually use 40 mg, twice per day.

Go to: Atorvastatin in cancer treatment

* Mebendazole a medicine used to treat a number of worms that can infest humans. It damages tubulin, which is in microtubules. These are found in parasites and cancer cells. Care Oncology usually use 100 mg per day for a month, then stop for a month during which time they use Doxycycline.

Go to: Mebendazole in cancer treatment

* Doxycycline a tetracycline antibiotic that is used to treat a wide variety of bacterial infections from acne to syphilis and from UTIs to gum disease. It is sometimes used to prevent malaria. There is a little research showing it can attack cancer stem cells. Care Oncology usually rotate this drug with Mebendazole one month each. The usual dose is 100 mg daily for a month.

Go to:Doxycycline in Cancer Treatment

Sometimes a fifth medicine is prescribed:

* Flarin is an anti-inflammatory for pain relief and is a lipid formulated ibuprofen. Care Oncology use a dose depending upon the situation of 200 - 400 mg 3 times per day.


Clinical Trial - The Metformin Protocol

As the best known drug, Metformin also sometimes gives its name to the protocol - The Metformin Protocol.

And, make no mistake, the metformin protocol is clearly positioned as an anti-cancer treatment protocol, despite the 1939 Cancer Act. The Doctors at Care Oncology will even sell you the medicines they prescribe.

The same four drugs are also used by the Care Oncology Doctors for all cancers from breast cancer to brain cancer, and from prostate cancer to leukaemia.

"The Care Oncology Clinic designed the COC protocol to complement and enhance the standard-of-care therapy."

You can take the protocol at the same time as you are taking orthodox medicine, or you can take the protocol on its own.


COC Protocol results?

So far, Care Oncology have only produced some results on Brain cancer Glioblastoma or GBM. Typically, survival post-operation is on average 15 months. Care Oncology claim to have doubled this.

Results have not been so forthcoming on other cancers

To quote the USA Care Oncology Website:

"Our 5-year study has shown that our adjunctive program may enhance the overall effect of conventional cancer treatment."

It is widely known that in the late 1990s, Professor Ben Williams beat his Brain cancer using Metformin, Mebendazole and Melatonin, in conjunction with two other off label drugs, Tamoxifen and Accutane. Mebendazole has clear research on its actions with brain cancer but limited research with other cancers.

For other cancers, it maybe that more flexibility is needed; certainly other off-label drugs can be useful with other cancers propranolol with Ovarian cancer, Dutasteride with Prostate, LDN with Colorectal cancer. Sometimes the useful drug is not licensed for use with Human. Animal parasite killer Fenbendazole appears to have more research on a larger variety of cancers than Mebendazole. We shall see.

Go to: Building an off label drugs protocol


The Care Oncology Clinic team

Care Oncology Clinic launched in 2014. Care Oncology has oncologists and Doctors in their clinic.

Care Concology, contact details -

COC Address:40 Harley St, Marylebone, London W1G 9PP

COC e-mail is: [email protected]

COC phone number is: +44 (0)20 3855 5939

They also have an operation now in the USA

Care Oncology USA

E mail:

US phone number: 800-392-1353


Care Oncology: 'changing the face of cancer treatment'?

Chris Woollams comments, "This is a tricky question. There is no doubt that Care Oncology have cause a widespread interest in off-label drugs (also called repurposed drugs). I have no doubt they have extended some survival times, and even saved lives.

Patients are interested because sometimes treatment options are limited from the start (GBM), and other times they are facing a 'terminal’ prognosis with little orthodox options left.

Doctors are interested because here are medications that can be used today they have been approved for use with humans. Why spend ten years inventing a new drug when one seems to exist already?

The basic premise starving a cancer is absolutely correct. For example, saying cancer patients should restrict glucose and stop glycolysis is nothing new of course the skeptics came after me for saying exactly this in 2011, two years before Care Oncology was born. But even now, Doctors and nurses in Hospitals bow to Big Sugar and the fizzy drinks manufacturers filling their Vending machines, and deny the truth!

So, all praise to COC for putting this out there and on the map.

I have one little concern and this is not a criticism at all of Care Oncology more a 'Side- effect’.

Increasingly patients are now talking about 'pathways’ or 'cancer pathways' and frankly, some are getting all wound up about them and which off-label drugs they should take. Facebook groups publish 'protocols’. A lot of the patients are running out of time and become quite aggressive when a layman like me says that I don’t know which off-label drug fits the pathway. (Frankly, I doubt most oncologists know any better.)

And drugs - especially adding four off-label ones to the three or four a patient already takes - can yield a dangerous mixture. No one should attempt this without professional supervision - go to Oncologists who understand the issues and drugs involved!

Be clear also: Very few off-label drugs have even good research, others have next to none, especially in human trials. Frankly, in some cases, there is far more research on the anti-cancer effects of Turmeric and Berberine. 

Bottom line this is not a DIY business. Nor should it be over-claimed. PLEASE - start at Care Oncology or an Integrative Oncologist who knows what these drugs do and how they might interact with those you are already taking.

Go to: Doxycycline an antibiotic that attacks cancer stem cells

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