Oesophageal cancer and aspirin

Oesophageal cancer and aspirin

Aspirin prevents and protects in cancer of the oesophagus - There has been great confusion over whether aspirin can cause problems in the esophagus (because it is known to cause stomach ulcers and bleeding), or whether its anti-inflammatory benefits reduce risk.

A meta-study found that aspirin had a both protective and preventative role in esophageal cancer. The study involved two cohort and seven case-controlled studies. Both Aspirin and Non-Steroidal Anti-Inflammatory Drug (NSAID) use was studied. Aspirin had a significant effect in protection; NSAIDs a borderline significant effect.

This study was completed in 2003 and there appear to be no newer studies. Aspirin and NSAIDs were associated with a lower risk of both Oesophageal Adenocarcinoma. EAC or OAC, and Oesophageal Squamous Cell Carcinoma, ESCC or OSCC.

Go to: Oesophageal Cancer Overview - symptoms, causes and treatment altrrnatives 

References

  1. https://www.ncbi.nlm.nih.gov/pubmed/12512029?dopt=Abstract

 

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