Modern prostate cancer treatment increases colorectal cancer risk

Modern prostate cancer treatment increases colorectal cancer risk

Research from scientists led by Dr. Yunxia Lu, Associate Professor in the Colorectal Surgery Dept. at the Karolinska Institute in Sweden has shown that since 1980, when prostate treatment with oestrogen was stopped, increases in colorectal cancer have been observed.

Research followed a large group of 149,743 prostate cancer patients, and compared them with the Swedish population at large. Patients after 1980 underwent treatments such as radical prostectomy, radiotherapy, androgen-deprivation therapy (ADT) and bilateral orchiectomy.

These patients all had increased risk of colorectal cancer of over 22% according to treatment type with some at 37%. Androgen-deprivation was felt to be the driver of the increased risk, with greater risk in the distal colon.

This was considered both a large and significant study.

Go To: Men over 55 gain no benefit from Prostate cancer treatment

Ref: Lui, Y et al, Cancer Control, April 2015


2016 Research
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