Curcumin suppresses HPV oncoproteins and restores the p53 gene

Curcumin suppresses HPV oncoproteins and restores the p53 gene
 

 

Curcumin has the ability to prevent Human papillomavirus creating cervical cancer cells. This important research finding (1) has the potential to help over 6 million Americans who are infected currently with HPV.

 

 

 

 

 

The study examined the pathways involved in developing cervical cancer and showed that curcumin inhibited tumorigenic factors such as cancer cell spread while inhibiting the transcription of HPV 16 as soon as 6 hours after presenting the curcumin.

 

 

 

 

 

What was really interesting was the ability of curcumin to restore three cancer tumour suppressor proteins - p53, retinoblastoma protein, and PTPN13.

 

 

 

 

 

Chris Woollams, former Oxford Biochemist and founder of CANCERactive said, “We are slowly but surely looking at the research available on HPV. The orthodox approach is to vaccinate girls as young as 13 and this has been highly controversial with clear evidence of damage to some unfortunate participants. There is no research on boys, who have a different biochemistry, yet there are vaccine lobbyists wanting to vaccinate them too. This work, alongside work on artemisinin and ellagic acid, explains why there are so few deaths when such a high level of the population in America becomes infected. It also offers an understanding of sensible alternatives to people who refuse to be brain washed by Pharma propaganda”.

 

 

 

 

 

In a second study (2) curcumin was shown to counter oestradiol, a form of oestrogen, known to drive the formation and proliferation of HPV cervical cancer cells.

 

 

 
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  1. Curcumin suppresses human papillomavirus oncoproteins, restores p53, Rb, and PTPN13 proteins and inhibits benzo[apyrene-induced upregulation of HPV E7. Maher DM, Bell MC, O’Donnell EA, Gupta BK, Jaggi M, Chauhan SC. (Mol Carcinog. 2011 Jan;50(1):47-57. doi: 10.1002/mc.20695).

  2. Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells. Singh M, Singh N. Mol Cell Biochem. 2011 Jan;347(1-2):1-11. doi: 10.1007/s11010-010-0606-3. Epub 2010 Oct 13. 

 

 

 

 

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